The 40mg format of True North Peptides' MOTS-C — the mitochondria-encoded peptide for AMPK activation, insulin sensitivity, and longevity research. Four times the quantity of the 10mg vial, same ≥99% purity. Built for longitudinal protocols, dose-response studies, or multi-cohort research designs. For research use only.
MOTS-C 40mg — For Serious Research Programs
Everything from the 10mg vial, four times over. Same MOTS-C, same ≥99% purity standard, same mitochondria-encoded peptide that's positioned at the cutting edge of longevity and metabolic research. The 40mg format is for researchers who need extended timelines, consistent batch-matched material, or are running dose-response investigations across multiple cohorts.
Why MOTS-C Is Different
Almost every peptide in the body is encoded by nuclear DNA. MOTS-C is encoded by mitochondrial DNA — the separate genome your mitochondria carry from ancient bacterial ancestors. This gives it a fundamentally different origin and mechanism: it's a signal from your mitochondria to your nucleus, activated under metabolic stress, that turns on AMPK and shifts your cells into a high-efficiency energy mode.
AMPK Activation, Exercise Adaptation, and Longevity
MOTS-C activates AMPK via folate cycle inhibition — a mechanism that distinguishes it from direct AMPK activators. It rises in circulation in response to exercise. It declines with age. And animal studies examining MOTS-C repletion show effects on age-related metabolic decline and lifespan. For researchers working at the intersection of mitochondrial biology, metabolic health, and longevity science, this is a primary research tool.
Product Specifications
Compound: MOTS-C (16-AA mitochondria-derived peptide) | Form: Lyophilised powder | Vial Size: 40mg | Purity: ≥99% | Storage: −20°C dry; 2–8°C post-reconstitution.
Store lyophilised product at -20°C or below. After reconstitution, store at 4°C and use within 30 days. Keep away from direct sunlight and moisture.
This product is intended for laboratory and research use only. Not for human or veterinary use. Must be handled by qualified researchers in an appropriate facility.